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The COVID-19 pandemic, caused by infection with SARS-CoV-2, has resulted in an enormous health and economic burden worldwide. This working model of international collaboration underscores what is possible for future genetic discoveries in emerging pandemics, or indeed for any complex human disease. The identification of novel host genetic factors associated with COVID-19 was made possible by the community of human genetics researchers coming together to prioritize the sharing of data, results, resources and analytical frameworks. Mendelian randomization analyses support a causal role for smoking and body-mass index for severe COVID-19 although not for type II diabetes. They also represent potentially actionable mechanisms in response to infection. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases 3, 4, 5, 6, 7. We report 13 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Here we describe the results of three genome-wide association meta-analyses that consist of up to 49,562 patients with COVID-19 from 46 studies across 19 countries. We formed a global network of researchers to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-19 1, 2, host genetics may also be important. Check out the latest issue of Metrosource available on newsstands or visit Metrosource.The genetic make-up of an individual contributes to the susceptibility and response to viral infection. On this episode, we chat with Randy and Fenton about the early days of World of Wonder, the evolution of drag, the reality of reality TV, the power of social media, breaking into Hollywood, their special relationship with RuPaul, DragCon, and their message to their fans for Pride…with host Alexander Rodriguez.
HA GAY MEME ORIGIN TV
What started out as a dream with barely any money to buy a fax machine has turned into a global conglomerate with award-winning TV shows, web series, live events, podcasts, films, and documentaries that have bridged the gap between LGBTQ+ and mainstream programming. The team celebrates 30-plus years since they founded the multi-media empire that is World of Wonder, responsible for some of our community’s most trailblazing queer content, giving voice to underrepresented artists, icons, and activists. This dynamic duo, along with their award-winning team, have not only made RuPaul’s Drag Race a mainstream success but have been designated by Variety for having the biggest impact in reality TV. Randy Barbato and Fenton Bailey are superheroes of reality TV. Want to know when we publish more articles like this one? Sign up for MetroEspresso. I have a thing for cartoon and comic dads. Nothing brings together a family like making fun of dad! Sometimes you’ve just gotta ask for what you want. Read Next | Wanda Sykes Out in a Netflix Stand-Up Special The One About Harry Potter
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Read Next | These Are 11 Reasons Milo Yiannopoulos Is Embarrassing The One About Gay Guys and Cute BoysĪre the straight women running because they fear the gays will beat them to him? Gays in high school going on dates with girls to prove they’re not gay from r/gaymemesĬlass, please open your textbooks to the page that begins, “Milk, milk, lemonade…”Īnd we thought the “Sexy Mister Rogers” costumes had gone too far…
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Read Next | These Are 9 Books That Will Make Gay Men Feel Better The One About Dating Girls in High School Would you happen to have anything slightly less fruited? I’m sorry, sir, but this cake is far too fruited for me.
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The One With the Suggestively Named Product Omg abac ahahah im always assigned top tho idk i think i just look top? Who knows im actually much more bottom than i seem tbh… from r/bisexual Waitress, I’d like to order a side of… feeling very attacked! “Tale as old as time, true as it can be…”